The Orton Plantation is a historic plantation house in Smithville Township in Brunswick County, North Carolina, United States. Located beside the Cape Fear River between Wilmington and Southport, Orton Plantation is considered to be a near-perfect example of Southern antebellum architecture. Built in 1735 by the co-founder of Brunswick Town, Colonel Maurice Moore, the Orton Plantation house is one of the oldest structures in Brunswick County.
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During its history Orton Plantation has been attacked by Native Americans, used as a military hospital, and been home to lawyers, physicians, military leaders, and a Colonial governor. On April 11, 1973, the Orton Plantation was added to the National Register of Historic Places. The Orton Plantation Gardens and family-owned chapel were open to the public until 2010, when the plantation was sold to Louis Moore Bacon, a direct decedent of the original builder.